Neuroimaging in genetic frontotemporal dementia and amyotrophic lateral sclerosis

Neuroimaging in genetic frontotemporal dementia and amyotrophic lateral sclerosis

Blog Article

Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) have a strong clinical, genetic and pathological Bulbs overlap.This review focuses on the current understanding of structural, functional and molecular neuroimaging signatures of genetic FTD and ALS.We overview quantitative neuroimaging studies on the most common genes associated with FTD (MAPT, GRN), ALS (SOD1), and both (C9orf72), and summarize visual observations Trivet Foot of images reported in the rarer genes (CHMP2B, TARDBP, FUS, OPTN, VCP, UBQLN2, SQSTM1, TREM2, CHCHD10, TBK1).